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Keywords: MYRF
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Journal Articles
In collection:
Heart Disease
Lino Doering, Alex Cornean, Thomas Thumberger, Joergen Benjaminsen, Beate Wittbrodt, Tanja Kellner, Omar T. Hammouda, Matthias Gorenflo, Joachim Wittbrodt, Jakob Gierten
Journal:
Disease Models & Mechanisms
Dis Model Mech (2023) 16 (8): dmm049811.
Published: 16 August 2023
... , cdc42bpab , ankrd11 and myrf , encoding a transcription factor recently linked to cardiac-urogenital syndrome. Our myrf mutant line showed particularly prominent embryonic cardiac defects recapitulating phenotypes of pediatric patients, including hypoplastic ventricle. Mimicking human mutations, we edited...
Includes: Supplementary data
