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Keywords: MEK1 Y130C mutation
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Journal Articles
In collection:
The RAS Pathway
Rifdat Aoidi, Nicolas Houde, Kim Landry-Truchon, Michael Holter, Kevin Jacquet, Louis Charron, Suguna Rani Krishnaswami, Benjamin D. Yu, Katherine A. Rauen, Nicolas Bisson, Jason Newbern, Jean Charron
Journal:
Disease Models & Mechanisms
Dis Model Mech (2018) 11 (3): dmm031278.
Published: 13 March 2018
..., including increased numbers of GFAP + astrocytes and Olig2 + oligodendrocytes in regions of the cerebral cortex. These data indicate that the Mek1 Y130C mutation recapitulates major aspects of CFC, providing a new animal model to investigate the physiopathology of this RASopathy. This article has...
Includes: Supplementary data