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Keywords: Lysyl oxidase
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Journal Articles
Dis Model Mech (2017) 10 (11): 1301–1312.
Published: 01 November 2017
... extracellular matrix [i.e. collagen cross-linking mediated by the lysyl oxidase (LO) family of enzymes (LOX, LOXL1-4)] might contribute to disease pathogenesis and represent a therapeutic target. This study aimed to further our understanding of the mechanisms by which LO inhibitors might improve lung fibrosis...
Includes: Supplementary data
Journal Articles
Dis Model Mech (2015) 8 (6): 543–551.
Published: 01 June 2015
... the pathophysiology of obesity. The lysyl oxidase (LOX) family of amine oxidases, including LOX and LOX-like (LOXL) isoenzymes, controls ECM maturation, and upregulation of LOX activity is essential in fibrosis; however, its involvement in adipose tissue dysfunction in obesity is unclear. In this...