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Keywords: Lynch syndrome
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Journal Articles
In collection:
Cancer Metabolism
Journal:
Disease Models & Mechanisms
Dis Model Mech (2023) 16 (8): dmm050240.
Published: 31 July 2023
... in Lynch syndrome (LS)-associated colorectal cancers. Here, we show that defective MMR (dMMR) interacts with acetaldehyde, in a gene/environment interaction, enhancing dMMR-driven colonic tumour formation in a LS murine model of Msh2 conditional inactivation (Lgr5-CreER ; Msh2 flox/− , or Msh2-LS) combined...
Includes: Supplementary data
