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Keywords: Luciferase assays
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Journal Articles
Journal:
Disease Models & Mechanisms
Dis Model Mech (2024) 17 (6): dmm050584.
Published: 5 July 2024
... to chondrogenesis. In canonical WNT luciferase assays using frontonasal mass cells, the variants had dominant-negative effects on wild-type FZD2 . In non-canonical assays, the 425C>T variant failed to activate the reporter above control levels and was unresponsive to exogenous WNT5A. This is the first single...
Includes: Supplementary data
