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1-2 of 2
Keywords: Lipogenesis
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Journal Articles
In collection:
Drosophila as a Disease Model
Journal:
Disease Models & Mechanisms
Dis Model Mech (2022) 15 (11): dmm049650.
Published: 14 November 2022
.... Here, using Drosophila as a model system, we observed that the phosphodeficient SREBP proteins (SREBP-Thr390Ala) were more stable and more potent in stimulating the expression of lipogenic genes and promoting lipogenesis in vivo than wild-type SREBP. In addition, starvation blocked the effects of wild...
Includes: Supplementary data
Journal Articles
Margarita Vida, Ana Luisa Gavito, Francisco Javier Pavón, Dolores Bautista, Antonia Serrano, Juan Suarez, Sergio Arrabal, Juan Decara, Miguel Romero-Cuevas, Fernando Rodríguez de Fonseca, Elena Baixeras
Journal:
Disease Models & Mechanisms
Dis Model Mech (2015) 8 (7): 721–731.
Published: 1 July 2015
... contribute to the aggravation of fatty liver disease through increasing lipogenesis. In contrast to WT mice, IL-6 −/− mice showed upregulation of hepatic TNFα when exposed to a HFD, but the rIL-6 treatment reduced this upregulation, which is consistent with previous data describing the role of IL-6...
Includes: Supplementary data
