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Keywords: Lineage tracing
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Journal Articles
Dis Model Mech (2022) 15 (9): dmm049566.
Published: 20 September 2022
... of cell populations over time. Here, we applied tamoxifen-inducible cre ERt2 /loxP lineage tracing to a zebrafish model of MITF-dependent melanoma regression and recurrence to image and trace cell populations in vivo through disease stages. Using this strategy, we show that melanoma persister cells...
Includes: Supplementary data
Journal Articles
Journal Articles
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Cancer Metabolism
Dis Model Mech (2020) 13 (7): dmm044768.
Published: 30 July 2020
... proliferative than non-labelled cells. Our results demonstrate that single-cell lineage tracing of hypoxic tumour cells can allow visualisation of their behaviour in living tumours using intravital microscopy. This tool should prove valuable for the study of dissemination and treatment response of post-hypoxic...
Includes: Supplementary data
Journal Articles
Journal Articles
In collection:
Cancer
Dis Model Mech (2016) 9 (2): 105–114.
Published: 1 February 2016
... . 10.1242/dmm.015974 Guest , R. V. , Boulter , L. , Kendall , T. J. , Minnis-Lyons , S. E. , Walker , R. , Wigmore , S. J. , Sansom , O. J. and Forbes , S. J. ( 2014 ). Cell lineage tracing reveals a biliary origin of intrahepatic cholangiocarcinoma . Cancer Res...
Journal Articles
Dis Model Mech (2014) 7 (7): 929–936.
Published: 1 July 2014
... use, distribution and reproduction in any medium provided that the original work is properly attributed. Mosaic analysis Microsatellite instability Lineage tracing Tumor induction Somatic mosaicism is a widely used term to describe the presence of two genetically different cell...
Includes: Supplementary data