... of regenerating their lower jaws; however, the underlying mechanisms and their similarities to those in limb regeneration are unknown. In this work, we used morphological, histological and transcriptomic approaches to analyze the regeneration of lateral resection defects in the axolotl mandible. We found...

...Brittany T. Truong; Lomeli C. Shull; Ezra Lencer; Eric G. Bend; Michael Field; Elizabeth E. Blue; Michael J. Bamshad; Cindy Skinner; David Everman; Charles E. Schwartz; Heather Flanagan-Steet; Kristin B. Artinger ABSTRACT Split hand/foot malformation (SHFM) is a rare limb abnormality with clefting...

...Xuming Zhu; Mingang Xu; N. Adrian Leu; Edward E. Morrisey; Sarah E. Millar ABSTRACT Human Robinow syndrome (RS) and dominant omodysplasia type 2 (OMOD2), characterized by skeletal limb and craniofacial defects, are associated with heterozygous mutations in the Wnt receptor FZD2. However, as FZD2...

...Mary P. Colasanto; Shai Eyal; Payam Mohassel; Michael Bamshad; Carsten G. Bonnemann; Elazar Zelzer; Anne M. Moon; Gabrielle Kardon ABSTRACT In the vertebrate limb over 40 muscles are arranged in a precise pattern of attachment via muscle connective tissue and tendon to bone and provide an extensive...