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Keywords: Light-sheet fluorescence microscopy
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Journal Articles
In collection:
Metabolic Disorders
Urmas Roostalu, Jacob Lercke Skytte, Casper Gravesen Salinas, Thomas Klein, Niels Vrang, Jacob Jelsing, Jacob Hecksher-Sørensen
Journal:
Disease Models & Mechanisms
Dis Model Mech (2020) 13 (12): dmm045351.
Published: 18 December 2020
... pancreatic exocrine cells to β-cells . Nature 455 , 627 - 632 . 10.1038/nature07314 Summary: We report a 3D quantitative imaging platform (using light-sheet fluorescence microscopy) that can reveal changes in beta cell volume and proliferation, and leukocyte infiltration in pancreata in mouse...
Includes: Supplementary data
Journal Articles
In collection:
Neurodegeneration: from Models to Mechanisms to Therapies
Urmas Roostalu, Casper B. G. Salinas, Ditte D. Thorbek, Jacob L. Skytte, Katrine Fabricius, Pernille Barkholt, Linu M. John, Vanessa Isabell Jurtz, Lotte Bjerre Knudsen, Jacob Jelsing, Niels Vrang, Henrik H. Hansen, Jacob Hecksher-Sørensen
Journal:
Disease Models & Mechanisms
Dis Model Mech (2019) 12 (11): dmm042200.
Published: 22 November 2019
... in central dopaminergic pathways, we used iDISCO immunolabeling, light-sheet fluorescence microscopy (LSFM) and deep-learning computational methods for whole-brain three-dimensional visualization and automated quantitation of tyrosine hydroxylase (TH)-positive neurons in the adult mouse brain. Mice...
Includes: Supplementary data
Journal Articles
In collection:
Zebrafish as a Disease Model
Journal:
Disease Models & Mechanisms
Dis Model Mech (2019) 12 (10): dmm040188.
Published: 25 October 2019
... and inaccuracies. We developed and validated a deep learning-based image-analysis platform for automated extraction of volumetric parameters of cardiac function from dynamic light-sheet fluorescence microscopy (LSFM) images of embryonic zebrafish hearts. This platform, the Cardiac Functional Imaging Network (CFIN...
Includes: Supplementary data
