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Keywords: Light-sheet fluorescence microscopy
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Journal Articles
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Metabolic Disorders
Dis Model Mech (2020) 13 (12): dmm045351.
Published: 18 December 2020
... pancreatic exocrine cells to β-cells . Nature   455 , 627 - 632 . 10.1038/nature07314 Summary: We report a 3D quantitative imaging platform (using light-sheet fluorescence microscopy) that can reveal changes in beta cell volume and proliferation, and leukocyte infiltration in pancreata in mouse...
Includes: Supplementary data
Journal Articles
Dis Model Mech (2019) 12 (11): dmm042200.
Published: 22 November 2019
... in central dopaminergic pathways, we used iDISCO immunolabeling, light-sheet fluorescence microscopy (LSFM) and deep-learning computational methods for whole-brain three-dimensional visualization and automated quantitation of tyrosine hydroxylase (TH)-positive neurons in the adult mouse brain. Mice...
Includes: Supplementary data
Journal Articles
Dis Model Mech (2019) 12 (10): dmm040188.
Published: 25 October 2019
... and inaccuracies. We developed and validated a deep learning-based image-analysis platform for automated extraction of volumetric parameters of cardiac function from dynamic light-sheet fluorescence microscopy (LSFM) images of embryonic zebrafish hearts. This platform, the Cardiac Functional Imaging Network (CFIN...
Includes: Supplementary data