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Keywords: Leucine-rich repeat kinase 2
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Journal Articles
Barbara Calamini, Nathalie Geyer, Nathalie Huss-Braun, Annie Bernhardt, Véronique Harsany, Pierrick Rival, May Cindhuchao, Dietmar Hoffmann, Sabine Gratzer
Journal:
Disease Models & Mechanisms
Dis Model Mech (2021) 14 (6): dmm048017.
Published: 11 June 2021
... neurons of the substantia nigra in the ventral midbrain. Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common genetic cause of late-onset PD identified to date, with G2019S being the most frequent LRRK2 mutation, which is responsible for up to 1-2% of sporadic PD and up to 6% of familial...
Includes: Supplementary data
