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Keywords: Laser-capture microdissection
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Journal Articles
Dis Model Mech (2021) 14 (10): dmm049086.
Published: 25 October 2021
... that glomeruli constitute only a small proportion of renal cortical cells and bulk RNAseq does not capture glomerulus-specific gene expression changes. Therefore, gene expression analysis applied to glomeruli isolated by laser-capture microdissection (LCM) improves the resolution of glomerular transcriptome...
Includes: Supplementary data
Journal Articles
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Dis Model Mech (2019) 12 (8): dmm040444.
Published: 08 August 2019
... RNA sequencing (RNAseq). We have recently established a protocol to isolate CAS and normal stroma from archival FFPE tumours using laser-capture microdissection followed by RNAseq. Using this approach, we have analysed stroma from 15 canine mCA. Our data reveal strong reprogramming of canine CAS. We...
Includes: Supplementary data