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Keywords: LY2090314
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Journal Articles
A 3D adipogenesis platform to study the fate of fibro/adipogenic progenitors in muscular dystrophies
In collection:
Neuromuscular Disease
Alessio Reggio, Francesca De Paolis, Salma Bousselmi, Felice Cicciarelli, Sergio Bernardini, Alberto Rainer, Dror Seliktar, Stefano Testa, Carmine Cirillo, Paolo Grumati, Stefano Cannata, Claudia Fuoco, Cesare Gargioli
Journal:
Disease Models & Mechanisms
Dis Model Mech (2023) 16 (6): dmm049915.
Published: 23 June 2023
... that LY2090314 interferes with a genuine adipogenic program acting as WNT surrogate for the stabilization of a competent β-catenin transcriptional complex. To predict the beneficial impact of LY2090314 in limiting ectopic deposition of fat in human muscles, we combined a poly-ethylene-glycol-fibrinogen...
Includes: Supplementary data
