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Keywords: Kinase
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Journal Articles

Hyperactivation of MEK1 in cortical glutamatergic neurons results in projection axon deficits and aberrant motor learning

In collection:
Rare Disease Translational Research
George R. Bjorklund, Katherina P. Rees, Kavya Balasubramanian, Lauren T. Hewitt, Kenji Nishimura, Jason M. Newbern
Journal: Disease Models & Mechanisms
Dis Model Mech (2024) 17 (6): dmm050570.
https://doi.org/10.1242/dmm.050570
Published: 2 July 2024
...George R. Bjorklund; Katherina P. Rees; Kavya Balasubramanian; Lauren T. Hewitt; Kenji Nishimura; Jason M. Newbern ABSTRACT Abnormal extracellular signal-regulated kinase 1/2 (ERK1/2, encoded by Mapk3 and Mapk1 , respectively) signaling is linked to multiple neurodevelopmental diseases, especially...
View articletitled, Hyperactivation of MEK1 in cortical glutamatergic neurons results in projection axon deficits and aberrant motor learning
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Includes: Supplementary data
Journal Articles

Caspase-resistant ROCK1 expression prolongs survival of Eµ-Myc B cell lymphoma mice

In collection:
Cancer
Katerina Mardilovich, Gregory Naylor, Linda Julian, Narisa Phinichkusolchit, Karen Keeshan, Karen Blyth, Michael F. Olson
Journal: Disease Models & Mechanisms
Dis Model Mech (2024) 17 (5): dmm050631.
https://doi.org/10.1242/dmm.050631
Published: 21 May 2024
... macrophage recruitment to the bone marrow and prolonged survival of Eµ-Myc lymphoma mice. ROCK1 Rho GTPase Apoptosis Cytoskeleton Kinase Lymphoma Cancer Research UK http://dx.doi.org/10.13039/501100000289 A10419 A18276 A29799 A17196 Canadian Institutes of Health...
View articletitled, Caspase-resistant ROCK1 expression prolongs survival of Eµ-Myc B cell lymphoma mice
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Includes: Supplementary data