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Keywords: Kidney
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Journal Articles
Journal Articles
Dis Model Mech (2024) 17 (2): dmm050447.
Published: 14 February 2024
...Scarlet Xiaoyan Wang; Andrea Streit ABSTRACT The association between ear and kidney anomalies has long been recognized. However, little is known about the underlying mechanisms. In the last two decades, embryonic development of the inner ear and kidney has been studied extensively. Here, we...
Journal Articles
Dis Model Mech (2023) 16 (12): dmm050342.
Published: 1 December 2023
...Julie Bejoy; Justin M. Farry; Eddie S. Qian; Curtis H. Dearing; Lorraine B. Ware; Julie A. Bastarache; Lauren E. Woodard ABSTRACT Sepsis-associated acute kidney injury is associated with high morbidity and mortality in critically ill patients. Cell-free hemoglobin (CFH) is released...
Includes: Supplementary data
Journal Articles
Journal Articles
Dis Model Mech (2019) 12 (4): dmm038604.
Published: 9 April 2019
...Alexandria T. M. Blackburn; Rachel K. Miller ABSTRACT Congenital anomalies of the kidney and urinary tract (CAKUT) occur in ∼1/500 live births and are a leading cause of pediatric kidney failure. With an average wait time of 3-5 years for a kidney transplant, the need is high for the development...
Journal Articles
Dis Model Mech (2017) 10 (6): 773–786.
Published: 1 June 2017
... and inherited renal disorders. However, the mechanisms of renal fibrosis are incompletely understood and we therefore explored these by establishing a mouse model for a renal tubular disorder, referred to as autosomal dominant tubulointerstitial kidney disease (ADTKD) due to missense uromodulin ( UMOD...
Includes: Supplementary data
Journal Articles
Dis Model Mech (2016) 9 (3): 235–244.
Published: 1 March 2016
... genes in the central nervous system, heart, liver and kidney, and provide examples of the use of these assays to address questions related to human diseases. These assays provide us with simple yet powerful tools to study the pathogenic mechanisms associated with human disease-causing genes. ERG...
Includes: Supplementary data
Journal Articles
Journal Articles