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Keywords: KCNJ8
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Journal Articles
In collection:
Zebrafish as a Disease Model
Federico Tessadori, Helen I. Roessler, Sanne M. C. Savelberg, Sonja Chocron, Sarah M. Kamel, Karen J. Duran, Mieke M. van Haelst, Gijs van Haaften, Jeroen Bakkers
Journal:
Disease Models & Mechanisms
Dis Model Mech (2018) 11 (10): dmm035469.
Published: 18 October 2018
... missense mutations in their zebrafish orthologous genes by combining CRISPR/Cas9 with a short template oligonucleotide. Three of these lines carry gain-of-function mutations in genes encoding the pore-forming (Kir6.1, KCNJ8 ) and regulatory (SUR2, ABCC9 ) subunits of an ATP-sensitive potassium channel (K...
Includes: Supplementary data