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Keywords: JNK signaling
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Journal Articles
Ajai J. Pulianmackal, Kiriaki Kanakousaki, Kerry Flegel, Olga G. Grushko, Ella Gourley, Emily Rozich, Laura A. Buttitta
Journal:
Disease Models & Mechanisms
Dis Model Mech (2022) 15 (3): dmm049234.
Published: 16 March 2022
... in tissues with reduced Nup98-96, counteracted by elevated apoptosis and aberrant signaling associated with chronic wounding. Reducing Nup98-96 function led to defects in protein synthesis that triggered JNK signaling and contributed to hallmarks of tumorigenesis when apoptosis was inhibited. We suggest...
Includes: Supplementary data
