...Mohamadamin Forouzandehmehr; Michelangelo Paci; Jari Hyttinen; Jussi T. Koivumäki ABSTRACT Interconnected mechanisms of ischemia and reperfusion (IR) has increased the interest in IR in vitro experiments using human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs). We developed...

... through epicardial erythropoietin delivery. Angiogenesis Growth factor Mesenchymal cardiac stem cells Ischemia Proliferation Signaling Ischemic heart failure is the leading cause of death in the modern world. Further insight into the cell-specific mechanisms in specific cardiac stem...

... induces erythropoietin to promote neuron survival ( Ostrowski et al., 2011 ), but another study indicated that HIF-1α promotes cell death in the context of cerebral ischemia via p53 ( Halterman et al., 1999 ). Although diabetes might have a complex repressive effect on the stabilization...

.... This mouse model of repetitive brain injury by rotational head acceleration-deceleration partially mimics the major pathophysiological and behavioral events that occur in children with AHT. The resultant hypoxia/ischemia suggests a potential mechanism underlying the secondary rotational acceleration...

... Ischemia Pressure ulcer Venous leg ulcer Chronic, non-healing wounds ( Box 1 ) can be debilitating for the affected individual and place a massive financial burden on healthcare systems. During the financial year 2005–2006, the total annual cost to Hull and East Yorkshire National Health Service...