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Keywords: Ischaemia-reperfusion
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Journal Articles
Mouse models of myocardial infarction: comparing permanent ligation and ischaemia-reperfusion
Open AccessIn collection:
Tools and Resources for Mouse Studies
Journal:
Disease Models & Mechanisms
Dis Model Mech (2020) 13 (11): dmm046565.
Published: 18 November 2020
... with a suture, or ischaemia-reperfusion (IR), where the LAD is temporarily occluded before removing the suture to restore blood flow and tissue reperfusion. PL results in the majority of the area at risk becoming infarcted, leading to significant apoptotic cell death and a large scar. Conversely, IR salvages...
