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Keywords: Intestinal stem cells
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Journal Articles
Anjali Bajpai, Taushif Ahmad Quazi, Hong-Wen Tang, Nishat Manzar, Virender Singh, Ashwani Thakur, Bushra Ateeq, Norbert Perrimon, Pradip Sinha
Journal:
Disease Models & Mechanisms
Dis Model Mech (2020) 13 (7): dmm044420.
Published: 23 July 2020
..., specifically their TONDU domain, competitively inhibit YAP-TEAD interaction, resulting in arrest of tumor growth. Here, we show that overexpression of the TONDU peptide or its oral uptake leads to suppression of Yki-driven intestinal stem cell tumors in the adult Drosophila midgut. In addition, comparative...
Includes: Supplementary data