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Keywords: Induced pluripotent stem cells (iPSCs)
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Journal Articles
In collection:
Rare Disease Translational Research
Fumihiko Fujii, Hikaru Kanemasa, Sayaka Okuzono, Daiki Setoyama, Ryoji Taira, Kousuke Yonemoto, Yoshitomo Motomura, Hiroki Kato, Keiji Masuda, Takahiro A. Kato, Shouichi Ohga, Yasunari Sakai
Journal:
Disease Models & Mechanisms
Dis Model Mech (2024) 17 (6): dmm050574.
Published: 2 July 2024
... cells resulted in excessive phosphorylation of ribosomal protein S6 (encoded by Rps6 ) and increased susceptibility to heat stress. In agreement with these findings, induced pluripotent stem cells (iPSCs) from a patient with the p.R756C variant were more vulnerable to heat stress than control iPSCs...
Includes: Supplementary data