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1-6 of 6
Keywords: Imaging
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Journal Articles
Journal:
Disease Models & Mechanisms
Dis Model Mech (2023) 16 (8): dmm050074.
Published: 1 August 2023
... currently accessible technology to study their fate in vivo involves fluorescent labelling of exogenous EVs followed by whole-animal imaging. Although this is not a new technology, its translation from studying the fate of whole cells to subcellular EVs requires adaptation of the labelling techniques...
Journal Articles
Journal:
Disease Models & Mechanisms
Dis Model Mech (2022) 15 (12): dmm049753.
Published: 22 December 2022
... time. Establishing a reliable method for longitudinal in vivo imaging of adult D. cerebrum while maintaining viability will allow in-depth image-based studies of various processes involved in development, disease onset and progression, wound healing, and aging in an intact live animal. Here, a method...
Includes: Supplementary data
Journal Articles
Journal:
Disease Models & Mechanisms
Dis Model Mech (2020) 13 (3): dmm042689.
Published: 30 March 2020
... research in sarcopenia – the age-related loss of muscle mass and function. Zebrafish Sarcopenia Aging Genome GWAS Muscle disease Imaging Israel Science Foundation 10.13039/501100003977 1121/19 Muscle health is an essential element of healthy life and successful aging...
Journal Articles
In collection:
Neurodegenerative Disorders
Urmas Roostalu, Casper B. G. Salinas, Ditte D. Thorbek, Jacob L. Skytte, Katrine Fabricius, Pernille Barkholt, Linu M. John, Vanessa Isabell Jurtz, Lotte Bjerre Knudsen, Jacob Jelsing, Niels Vrang, Henrik H. Hansen, Jacob Hecksher-Sørensen
Journal:
Disease Models & Mechanisms
Dis Model Mech (2019) 12 (11): dmm042200.
Published: 22 November 2019
... 3D imaging is ideal for unbiased automated counting and densitometric analysis of TH-positive cells. The LSFM–deep learning pipeline tracked brain-wide changes in catecholaminergic pathways in the MPTP mouse model of PD, and may be applied for preclinical characterization of compounds targeting...
Includes: Supplementary data
Journal Articles
Mark R. Cronan, Allison F. Rosenberg, Stefan H. Oehlers, Joseph W. Saelens, Dana M. Sisk, Kristen L. Jurcic Smith, Sunhee Lee, David M. Tobin
Journal:
Disease Models & Mechanisms
Dis Model Mech (2015) 8 (12): 1643–1650.
Published: 1 December 2015
... infection requires dissection of adult organs or ex vivo isolation of immune cells. Recently, CLARITY and PACT (passive clarity technique) methodologies have enabled clearing and direct visualization of dissected organs. Here, we show that these techniques can be applied to image host-pathogen interactions...
Includes: Supplementary data
Journal Articles
Wolfgang J. Weninger, Stefan H. Geyer, Alexandrine Martineau, Antonella Galli, David J. Adams, Robert Wilson, Timothy J. Mohun
Journal:
Disease Models & Mechanisms
Dis Model Mech (2014) 7 (10): 1143–1152.
Published: 1 October 2014
...Wolfgang J. Weninger; Stefan H. Geyer; Alexandrine Martineau; Antonella Galli; David J. Adams; Robert Wilson; Timothy J. Mohun The arrival of simple and reliable methods for 3D imaging of mouse embryos has opened the possibility of analysing normal and abnormal development in a far more systematic...
Includes: Supplementary data