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Keywords: Huntington disease
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Journal Articles

Integrated multi-omics analysis of Huntington disease identifies pathways that modulate protein aggregation

Open Access
In collection:
Neuromuscular Disease
Sai S. Pradhan, Sai M. Thota, Saiswaroop Rajaratnam, Sai K. S. Bhagavatham, Sujith K. Pulukool, Sriram Rathnakumar, Kanikaram S. Phalguna, Rajesh B. Dandamudi, Ashish Pargaonkar, Prasanth Joseph, E. V. Joshy, Venketesh Sivaramakrishnan
Journal: Disease Models & Mechanisms
Dis Model Mech (2022) 15 (10): dmm049492.
https://doi.org/10.1242/dmm.049492
Published: 31 October 2022
...Sai S. Pradhan; Sai M. Thota; Saiswaroop Rajaratnam; Sai K. S. Bhagavatham; Sujith K. Pulukool; Sriram Rathnakumar; Kanikaram S. Phalguna; Rajesh B. Dandamudi; Ashish Pargaonkar; Prasanth Joseph; E. V. Joshy; Venketesh Sivaramakrishnan ABSTRACT Huntington disease (HD) is a neurodegenerative disease...
View articletitled, Integrated multi-omics analysis of Huntington disease identifies pathways that modulate protein aggregation
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Includes: Supplementary data
Journal Articles

Huntington disease iPSCs show early molecular changes in intracellular signaling, the expression of oxidative stress proteins and the p53 pathway

Open Access
Wojciech J. Szlachcic, Pawel M. Switonski, Wlodzimierz J. Krzyzosiak, Marek Figlerowicz, Maciej Figiel
Journal: Disease Models & Mechanisms
Dis Model Mech (2015) 8 (9): 1047–1057.
https://doi.org/10.1242/dmm.019406
Published: 1 September 2015
...Wojciech J. Szlachcic; Pawel M. Switonski; Wlodzimierz J. Krzyzosiak; Marek Figlerowicz; Maciej Figiel ABSTRACT Huntington disease (HD) is a brain disorder characterized by the late onset of motor and cognitive symptoms, even though the neurons in the brain begin to suffer dysfunction...
View articletitled, Huntington disease iPSCs show early molecular changes in intracellular signaling, the expression of oxidative stress proteins and the p53 pathway
Open the PDF for Huntington disease iPSCs show early molecular changes in intracellular signaling, the expression of oxidative stress proteins and the p53 pathway in another window
Includes: Supplementary data