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Keywords: Human induced pluripotent stem cells
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Journal Articles
Dis Model Mech (2023) 16 (12): dmm049861.
Published: 11 December 2023
... of human induced pluripotent stem cells to generate human microglia-like (hiMGL) cells heterozygous for three different NF1 gene mutations found in patients with NF1. Whereas all NF1 -mutant and isogenic control hiMGL cells expressed classical microglia markers and exhibited similar transcriptomes...
Includes: Supplementary data
Journal Articles
Journal Articles
Dis Model Mech (2016) 9 (1): 81–90.
Published: 1 January 2016
... available cellular models preclude deciphering the consequences of PCSK9 mutation further. We aimed to validate urine-sample-derived human induced pluripotent stem cells (UhiPSCs) as an appropriate tool to model PCSK9-mediated ADH and FHBL. To achieve our goal, urine-sample-derived somatic cells were...
Includes: Supplementary data