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1-2 of 2
Keywords: Histone modification
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Journal Articles
Altered expression, but small contribution, of the histone demethylase KDM6A in obstructive uropathy in mice
Open AccessLisa Y. Q. Hong, Emily S. H. Yeung, Duc Tin Tran, Veera Ganesh Yerra, Harmandeep Kaur, M. D. Golam Kabir, Suzanne L. Advani, Youan Liu, Sri Nagarjun Batchu, Andrew Advani
Journal:
Disease Models & Mechanisms
Dis Model Mech (2023) 16 (9): dmm049991.
Published: 1 September 2023
.... However, knockout of KDM6A in male mice causes only subtle changes, characterized by augmented inflammation. Epigenetic Histone modification KDM6A Inflammation Tubule cell PPAR Unilateral ureteral obstruction Canadian Institutes of Health Research http://dx.doi.org/10.13039...
Includes: Supplementary data
Journal Articles
Auditory hair cell defects as potential cause for sensorineural deafness in Wolf-Hirschhorn syndrome
Open Access
Journal:
Disease Models & Mechanisms
Dis Model Mech (2015) 8 (9): 1027–1035.
Published: 1 September 2015
..., the authors show that, although cochlear hair cells are specified normally in a WHS mouse model, they are disorganised and display sterocilia defects. Deafness Ear Hair cells Histone modification Methyltransferase Mouse Stereocilia Epigenetic processes, including histone modifications...
Includes: Supplementary data