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Keywords: Heterotopia
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Journal Articles
Marie Mayrhofer, Victor Gourain, Markus Reischl, Pierre Affaticati, Arnim Jenett, Jean-Stephane Joly, Matteo Benelli, Francesca Demichelis, Pietro Luigi Poliani, Dirk Sieger, Marina Mione
Journal:
Disease Models & Mechanisms
Dis Model Mech (2017) 10 (1): 15–28.
Published: 1 January 2017
... developmental disorders. We developed a zebrafish model of brain tumours based on somatic expression of oncogenes that activate MAPK and PI3K signalling in neural progenitor cells and found that HRAS V12 was the most effective in inducing both heterotopia and invasive tumours. Tumours, but not heterotopias...
Includes: Supplementary data