...Cheng Tian; Liyuan Li; Li Fan; Anthony Brown; Eric J. Norris; Michelle Morrison; Evan S. Glazer; Liqin Zhu ABSTRACT Various 3D models of hepatocytes (HCs) have been established to assess liver functions in vitro . The contribution of the hepatic non-parenchymal cells (NPCs), however, is largely...

...-specific Bscl2 -deficient mice from metabolic disease. To investigate this, we generated a novel mouse model in which Bscl2 has been deleted in both adipose tissue and hepatocytes simultaneously using an adeno-associated viral vector. Despite achieving efficient disruption of Bscl2 in the liver, hepatic...