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Keywords: Hepatic stellate cells
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Journal Articles
Dis Model Mech (2021) 14 (5): dmm048884.
Published: 20 May 2021
... by sinusoidal endothelial cells (LSEC) induce hepatic stellate cell (HSC) contraction and contribute to portal hypertension (PH). Statins improve LSEC function, and ambrisentan is a selective endothelin-receptor-A antagonist. We aimed to analyse the combined effects of atorvastatin and ambrisentan on liver...
Includes: Supplementary data
Journal Articles
Dis Model Mech (2019) 12 (7): dmm038810.
Published: 16 July 2019
...) and Irs2 -deficient (IRS2KO) female mice. Histological and biochemical analyses, together with fibrogenic and inflammatory responses were evaluated in livers from mice at 3, 7 and 28 days following BDL. We also explored whether activation of human hepatic stellate cells (HSCs) induced by IGF1 was modulated...
Includes: Supplementary data
Journal Articles
Dis Model Mech (2016) 9 (11): 1383–1396.
Published: 1 November 2016
... zebrafish larvae to 2% ethanol for 24 h induced hepatic steatosis, angiogenesis and fibrogenesis. The liver started self-repair once ethanol was removed. Although inhibiting Kdrl did not block the initial activation of hepatic stellate cells during ethanol treatment, it suppressed their proliferation...
Includes: Supplementary data