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Keywords: HIV-1
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Journal Articles
Mackenzie Thornton, Nicole Sommer, Mercedes McGonigle, Anil Kumar Ram, Sireesha Yerrathota, Henrietta Ehirim, Aakriti Chaturvedi, Johnny Dinh Phan, Anubhav Chakraborty, Praveen V. Chakravarthi, Sumedha Gunewardena, Mudit Tyagi, Jaya Talreja, Tao Wang, Pravin Singhal, Pamela V. Tran, Timothy A. Fields, Patricio E. Ray, Navneet K. Dhillon, Madhulika Sharma
Journal:
Disease Models & Mechanisms
Dis Model Mech dmm.052056.
Published: 6 February 2025
... A. Fields; Patricio E. Ray; Navneet K. Dhillon; Madhulika Sharma Antiretroviral therapy (ART) has decreased HIV-1 associated morbidity. However, despite ART, immune cells remain latently infected leading to chronic inflammation and HIV-1 associated comorbidities. New strategies are needed to target viral...
Journal Articles
Journal:
Disease Models & Mechanisms
Dis Model Mech (2020) 13 (10): dmm045641.
Published: 28 October 2020
... is established in children, it is difficult to revert its long-term progression, and we need better animal models of childhood HIVAN to test new treatments. To define whether the HIV-1 trans-activator ( Tat ) gene precipitates HIVAN in young mice, and to develop an inducible mouse model of childhood HIVAN...
Includes: Supplementary data
Journal Articles
In collection:
Stem Cells
Journal:
Disease Models & Mechanisms
Dis Model Mech (2017) 10 (12): 1489–1502.
Published: 1 December 2017
...Weizhe Li; Santhi Gorantla; Howard E. Gendelman; Larisa Y. Poluektova ABSTRACT Studies of innate glial cell responses for progressive human immunodeficiency virus type one (HIV-1) infection are limited by a dearth of human disease-relevant small-animal models. To overcome this obstacle, newborn NOD...
Includes: Supplementary data