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Keywords: HIF1A
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Journal Articles
In collection:
The RAS Pathway
Dis Model Mech (2022) 15 (2): dmm048953.
Published: 19 November 2021
... hypoxia pathway genes HIF1A and ARNT ( HIF1B ). The drug screen revealed that echinomycin, an inhibitor of HIF1A, can effectively attenuate the leukemia phenotype caused by KRAS G12V . Furthermore, we showed that echinomycin treatment can effectively suppress oncogenic RAS -driven leukemia cell...
Includes: Supplementary data