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Keywords: HHT
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Journal Articles

Deficiency in hereditary hemorrhagic telangiectasia-associated Endoglin elicits hypoxia-driven heart failure in zebrafish

In collection:
Heart Disease
Etienne Lelièvre, Charlotte Bureau, Yann Bordat, Maxence Frétaud, Christelle Langevin, Chris Jopling, Karima Kissa
Journal: Disease Models & Mechanisms
Dis Model Mech (2023) 16 (5): dmm049488.
https://doi.org/10.1242/dmm.049488
Published: 2 June 2023
...Etienne Lelièvre; Charlotte Bureau; Yann Bordat; Maxence Frétaud; Christelle Langevin; Chris Jopling; Karima Kissa ABSTRACT Hereditary hemorrhagic telangiectasia (HHT) is a rare genetic disease caused by mutations affecting components of bone morphogenetic protein (BMP)/transforming growth factor-β...
View article titled, Deficiency in hereditary hemorrhagic telangiectasia-associated Endoglin elicits hypoxia-driven heart failure in zebrafish
Open the PDF for Deficiency in hereditary hemorrhagic telangiectasia-associated Endoglin elicits hypoxia-driven heart failure in zebrafish in another window
Includes: Supplementary data
Journal Articles

Therapeutic targeting of vascular malformation in a zebrafish model of hereditary haemorrhagic telangiectasia

In collection:
Rare Disease Translational Research , Zebrafish as a Disease Model
Ryan O. Snodgrass, Karan Govindpani, Karen Plant, Elisabeth C. Kugler, Changmin Doh, Thomas Dawson, Luis E. McCormack, Helen M. Arthur, Timothy J. A. Chico
Journal: Disease Models & Mechanisms
Dis Model Mech (2023) 16 (4): dmm049567.
https://doi.org/10.1242/dmm.049567
Published: 30 March 2023
...Ryan O. Snodgrass; Karan Govindpani; Karen Plant; Elisabeth C. Kugler; Changmin Doh; Thomas Dawson; Luis E. McCormack; Helen M. Arthur; Timothy J. A. Chico ABSTRACT Hereditary haemorrhagic telangiectasia (HHT) causes arteriovenous malformations (AVMs) in multiple organs to cause bleeding...
View article titled, Therapeutic targeting of vascular malformation in a zebrafish model of hereditary haemorrhagic telangiectasia
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Includes: Supplementary data
Journal Articles

Soluble endoglin regulates expression of angiogenesis-related proteins and induction of arteriovenous malformations in a mouse model of hereditary hemorrhagic telangiectasia

Eunate Gallardo-Vara, Simon Tual-Chalot, Luisa M. Botella, Helen M. Arthur, Carmelo Bernabeu
Journal: Disease Models & Mechanisms
Dis Model Mech (2018) 11 (9): dmm034397.
https://doi.org/10.1242/dmm.034397
Published: 21 September 2018
... depends on expression of endogenous membrane-bound endoglin. Angiogenesis Endoglin HHT AVM TGF-β Endothelial cells Ministerio de Economía, Industria y Competitividad, Gobierno de España 10.13039/501100010198 SAF2010-19222 SAF2013-43421-R EEBB-I-14-09020 EEBB-I-15-10398...
View article titled, Soluble endoglin regulates expression of angiogenesis-related proteins and induction of arteriovenous malformations in a mouse model of hereditary hemorrhagic telangiectasia
Open the PDF for Soluble endoglin regulates expression of angiogenesis-related proteins and induction of arteriovenous malformations in a mouse model of hereditary hemorrhagic telangiectasia in another window
Includes: Supplementary data