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1-2 of 2
Keywords: HER2
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Journal Articles
In collection:
Cancer
Liliana D. Ordonez, Lorenzo Melchor, Kirsty R. Greenow, Howard Kendrick, Giusy Tornillo, James Bradford, Peter Giles, Matthew J. Smalley
Journal:
Disease Models & Mechanisms
Dis Model Mech (2021) 14 (5): dmm048736.
Published: 18 May 2021
...-initiating genetic lesions cooperate to influence mammary tumour phenotype. Here, we use a CRE-activated HER2 orthologue to specifically target HER2/ERBB2 oncogenic activity to basal or luminal ER − mammary epithelial cells and perform a detailed analysis of the tumours that develop. We find...
Includes: Supplementary data
Journal Articles
In collection:
Cancer
Helen Creedon, Lucy A. Balderstone, Morwenna Muir, Jozef Balla, Laura Gomez-Cuadrado, Natasha Tracey, Joseph Loane, Teresa Klinowska, William J. Muller, Valerie G. Brunton
Journal:
Disease Models & Mechanisms
Dis Model Mech (2016) 9 (2): 131–140.
Published: 1 February 2016
...Helen Creedon; Lucy A. Balderstone; Morwenna Muir; Jozef Balla; Laura Gomez-Cuadrado; Natasha Tracey; Joseph Loane; Teresa Klinowska; William J. Muller; Valerie G. Brunton ABSTRACT Resistance to human epidermal growth factor receptor 2 (HER2)-targeted therapies presents a major clinical problem...
Includes: Supplementary data
