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In collection:Zebrafish as a Disease Model
Annekatrien Boel, Hanna De Saffel, Wouter Steyaert, Bert Callewaert, Anne De Paepe, Paul J. Coucke, Andy Willaert
Journal: Disease Models & Mechanisms
Dis Model Mech (2018) 11 (10): dmm035352.
Published: 18 October 2018
... repair (HDR) suffers from low efficiency, impeding its use for high-throughput knock-in disease modeling. In this study, we used next-generation sequencing (NGS) analysis to determine the efficiency and reliability of CRISPR/Cas9-mediated HDR using several types of single-stranded oligodeoxynucleotide...
Includes: Supplementary data