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Keywords: HD yeast model
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Journal Articles
Integrated multi-omics analysis of Huntington disease identifies pathways that modulate protein aggregation
Open AccessIn collection:
Neuromuscular Disease
Sai S. Pradhan, Sai M. Thota, Saiswaroop Rajaratnam, Sai K. S. Bhagavatham, Sujith K. Pulukool, Sriram Rathnakumar, Kanikaram S. Phalguna, Rajesh B. Dandamudi, Ashish Pargaonkar, Prasanth Joseph, E. V. Joshy, Venketesh Sivaramakrishnan
Journal:
Disease Models & Mechanisms
Dis Model Mech (2022) 15 (10): dmm049492.
Published: 31 October 2022
... in any medium provided that the original work is properly attributed. Summary: Metabolomic analysis of Huntington disease (HD) patients and of a HD yeast model identified deregulated metabolic pathways. We used the yeast model to investigate their role in the aggregation of huntingtin protein...
Includes: Supplementary data