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Keywords: H19
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Journal Articles
Modeling human epigenetic disorders in mice: Beckwith-Wiedemann syndrome and Silver-Russell syndrome
Journal:
Disease Models & Mechanisms
Dis Model Mech (2020) 13 (5): dmm044123.
Published: 26 May 2020
... of truncation cassettes. Figures are not drawn to scale. Centromeric to the human H19 / IGF2 cluster ( Fig. 2 A) and telomeric to the mouse cluster ( Fig. 2 B) is the CDKN1C / KCNQ1OT1 cluster. The ICR of this cluster (designated as IC2 in humans and as KvDMR1 in mice) and its regulatory mechanisms...