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Journal: Disease Models & Mechanisms
Dis Model Mech (2014) 7 (12): 1335–1340.
Published: 1 December 2014
... a delay in endoplasmic reticulum (ER)-to-Golgi transport and a reduction in the number of cargo vesicles leaving the trans-Golgi network. In addition, we found that huntingtin is required for secretory vesicle fusion at the plasma membrane. Similar defects in the early exocytic pathway were observed...
Includes: Supplementary data