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Keywords: Gene regulation
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Journal Articles

Altered binding affinity of SIX1-Q177R correlates with enhanced WNT5A and WNT pathway effector expression in Wilms tumor

Open Access
Matthew J. Stevenson, Sabrina K. Phanor, Urvi Patel, Stephen S. Gisselbrecht, Martha L. Bulyk, Lori L. O'Brien
Journal: Disease Models & Mechanisms
Dis Model Mech (2023) 16 (11): dmm050208.
https://doi.org/10.1242/dmm.050208
Published: 17 November 2023
View articletitled, Altered binding affinity of SIX1-Q177R correlates with enhanced WNT5A and WNT pathway effector expression in Wilms tumor
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Includes: Supplementary data
Journal Articles

The role of noncoding mutations in blood cancers

Open Access
In collection:
Cancer
Sunniyat Rahman, Marc R. Mansour
Journal: Disease Models & Mechanisms
Dis Model Mech (2019) 12 (11): dmm041988.
https://doi.org/10.1242/dmm.041988
Published: 26 November 2019
...-characterised examples of noncoding mutations in haematological malignancies, and highlight how a significant majority of these variants impinge on gene regulation through the formation of aberrant enhancers and promoters. We delve into the challenges faced by those that embark on a search for noncoding driver...
View articletitled, The role of noncoding mutations in blood cancers
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