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1-2 of 2
Keywords: GPA33
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Journal Articles
Michael Buchert, Franziska Rohde, Moritz Eissmann, Niall Tebbutt, Ben Williams, Chin Wee Tan, Alexander Owen, Yumiko Hirokawa, Alexandra Gnann, Gertraud Orend, Gayle Orner, Rod H. Dashwood, Joan K. Heath, Matthias Ernst, Klaus-Peter Janssen
Journal:
Disease Models & Mechanisms
Dis Model Mech (2015) 8 (11): 1361–1373.
Published: 1 November 2015
... to express throughout the intestinal epithelium a degradation-resistant β-catenin ( Ctnnb1 ), which lacks the first 131 amino acids, we inserted an epitope-tagged ΔN(1-131)-β-catenin-encoding cDNA as a knock-in transgene into the endogenous gpA33 gene locus in mice. The resulting gpA33 ΔN-Bcat mice showed...
Includes: Supplementary data
Journal Articles
Benjamin B. Williams, Niall C. Tebbutt, Michael Buchert, Tracy L. Putoczki, Karen Doggett, Shisan Bao, Cameron N. Johnstone, Frederick Masson, Frederic Hollande, Antony W. Burgess, Andrew M. Scott, Matthias Ernst, Joan K. Heath
Journal:
Disease Models & Mechanisms
Dis Model Mech (2015) 8 (8): 805–815.
Published: 1 August 2015
... function contributes to multiple gastrointestinal disorders, including food hypersensitivity, inflammatory bowel disease (IBD) and colitis-associated cancer (CAC). Glycoprotein A33 (GPA33) is an intestinal epithelium-specific cell surface marker and member of the CTX group of transmembrane proteins. Roles...
Includes: Supplementary data