... is induced by secretion of GABA from GABAergic motor neurons ( Fig. 3 A). The coordinated action of these neurotransmitters is essential for the contraction and relaxation cycles that drive the sinusoidal movement of C. elegans ( Jorgensen and Nonet, 1995 ; Richmond and Jorgensen, 1999 ). Fig. 3...

.... Mutations in genes involved in gamma-aminobutyric acid (GABA)-mediated inhibitory neurotransmission have been associated with a broad range of epilepsy syndromes. Mutations in the GABA-A receptor gamma 2 subunit gene ( GABRG2 ), for example, have been associated with absence epilepsy and febrile seizures...