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Keywords: Fibroblasts
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Journal Articles
Dis Model Mech (2021) 14 (8): dmm048995.
Published: 25 August 2021
... by stable depletion of TFAM in primary mouse skin fibroblasts (SK-FBs) after 4-hydroxytamoxifen (4-OHT) administration. Tfam gene deletion caused a sustained reduction in Tfam and mtDNA-encoded mRNA in Cre(+) SK-FBs cultured for low (LP) and high (HP) passages that translated into a loss of TFAM protein...
Includes: Supplementary data
Journal Articles
Dis Model Mech (2018) 11 (4): dmm029447.
Published: 19 April 2018
...-associated fibroblasts, a highly abundant and heterogeneous population of cells of mesenchymal lineage. Although it is known that fibroblasts are present from the tumor's inception to the end-stage metastatic spread, their precise functional role in cancer is not fully understood. It has been suggested...
Includes: Supplementary data
Journal Articles
Journal Articles
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In collection:
Cancer
Dis Model Mech (2017) 10 (1): 39–52.
Published: 1 January 2017
...Zhaohui Yang; Yu-Ching Peng; Anuradha Gopalan; Dong Gao; Yu Chen; Alexandra L. Joyner ABSTRACT It is widely appreciated that reactive stroma or carcinoma-associated fibroblasts can influence epithelial tumor progression. In prostate cancer (PCa), the second most common male malignancy worldwide...
Includes: Supplementary data