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1-3 of 3
Keywords: Fatty liver disease
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Journal Articles
Jens Tiefenbach, Lilia Magomedova, Jiabao Liu, Arkadiy A. Reunov, Ricky Tsai, Neena S. Eappen, Rebecca A. Jockusch, Corey Nislow, Carolyn L. Cummins, Henry M. Krause
Journal:
Disease Models & Mechanisms
Dis Model Mech (2018) 11 (9): dmm034801.
Published: 31 August 2018
... redox to the two receptors. Testing idebenone in a mouse model of type 2 diabetes revealed the ability to reverse fatty liver development. These findings indicate new mechanisms of action for both PPARα and PPARγ, and new potential treatment options for nonalcoholic fatty liver disease (NAFLD...
Includes: Supplementary data
Journal Articles
In collection:
Zebrafish as a Disease Model
Kathryn Bambino, Chi Zhang, Christine Austin, Chitra Amarasiriwardena, Manish Arora, Jaime Chu, Kirsten C. Sadler
Journal:
Disease Models & Mechanisms
Dis Model Mech (2018) 11 (2): dmm031575.
Published: 26 February 2018
...Kathryn Bambino; Chi Zhang; Christine Austin; Chitra Amarasiriwardena; Manish Arora; Jaime Chu; Kirsten C. Sadler ABSTRACT The rapid increase in fatty liver disease (FLD) incidence is attributed largely to genetic and lifestyle factors; however, environmental toxicants are a frequently overlooked...
Includes: Supplementary data
Journal Articles
Ana M. Vacaru, Antonio Fabio Di Narzo, Deanna L. Howarth, Orkhontuya Tsedensodnom, Dru Imrie, Ayca Cinaroglu, Salma Amin, Ke Hao, Kirsten C. Sadler
Journal:
Disease Models & Mechanisms
Dis Model Mech (2014) 7 (7): 823–835.
Published: 1 July 2014
.... Fatty liver disease (steatosis) is associated with markers of UPR activation and robust UPR induction can cause steatosis; however, in other cases, UPR activation can protect against this disease. By assessing the magnitude of activation of UPR sensors and target genes in the liver of zebrafish larvae...
Includes: Supplementary data