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Keywords: FUS
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Journal Articles
Dis Model Mech (2019) 12 (8): dmm040238.
Published: 13 August 2019
... stages of disease progression remains to be established in other ALS models. Here, we assessed vascular integrity in vivo throughout different disease stages, and investigated whether ANG treatment reverses vascular regression and prolongs motor neuron survival in the FUS (1-359) mouse model of ALS...
Includes: Supplementary data
Journal Articles
Journal Articles
Dis Model Mech (2014) 7 (10): 1175–1184.
Published: 1 October 2014
...-43, FUS and α-synuclein, as well as missense mutant versions of these proteins that cause neurodegenerative disease. Potentiated Hsp104 variants also rescue toxicity and aggregation of TAF15 but not EWSR1, two RNA-binding proteins with a prion-like domain that are connected with the development...