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Keywords: FOP
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Journal Articles
In collection:
Drug Discovery
Serena Cappato, Laura Tonachini, Francesca Giacopelli, Mario Tirone, Luis J. V. Galietta, Martina Sormani, Anna Giovenzana, Antonello E. Spinelli, Barbara Canciani, Silvia Brunelli, Roberto Ravazzolo, Renata Bocciardi
Journal:
Disease Models & Mechanisms
Dis Model Mech (2016) 9 (6): 685–696.
Published: 1 June 2016
... (BMPs). Activating mutations in ACVR1 are responsible for fibrodysplasia ossificans progressiva (FOP), a rare disease characterized by congenital toe malformation and progressive heterotopic endochondral ossification leading to severe and cumulative disability. Until now, no therapy has been available...
Includes: Supplementary data
