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Keywords: Exocytosis
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Journal Articles
Dis Model Mech (2018) 11 (9): dmm033449.
Published: 13 September 2018
... to Str N471D . At the cellular level, Str − cells displayed defects in cell growth, phagocytosis, macropinocytosis, exocytosis and lysosomal function. Expression of Str WT -GFP in Str − cells rescued all observed defects. In contrast, expression of Str N471D -GFP could not rescue lysosome morphology...
Includes: Supplementary data
Journal Articles
Dis Model Mech (2014) 7 (12): 1335–1340.
Published: 1 December 2014
... accumulation of mutant huntingtin protein, loss of wild-type huntingtin function might also contribute to neuronal cell death, but its precise function is not well understood. Therefore, we investigated the molecular role of huntingtin in exocytosis and observed that huntingtin knockdown in HeLa cells causes...
Includes: Supplementary data