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Keywords: Erythropoiesis
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Journal Articles
Dis Model Mech (2018) 11 (5): dmm034678.
Published: 21 May 2018
... erythropoiesis. Here, we describe a recessive mouse strain, called RBC19, harbouring a point mutation within the housekeeping gene, Tpi1 , which encodes the glycolysis enzyme, triosephosphate isomerase (TPI). A serine in place of a phenylalanine at amino acid 57 severely diminishes enzyme activity in red blood...