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Tayeba Khan, Kerstin W. Sinkevicius, Sylvia Vong, Arlen Avakian, Markley C. Leavitt, Hunter Malanson, Andre Marozsan, Kim L. Askew
Journal: Disease Models & Mechanisms
Dis Model Mech (2018) 11 (10): dmm035691.
Published: 08 October 2018
... ectonucleotide pyrophosphatase phosphodiesterase 1 ( ENPP1 ), which normally hydrolyzes extracellular ATP into AMP and pyrophosphate (PP i ). The disease is characterized by extensive arterial calcification and stenosis of large- and medium-sized vessels, leading to vascular-related complications of hypertension...
Includes: Supplementary data