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Keywords: Endothelium
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Journal Articles
Dis Model Mech (2023) 16 (10): dmm050361.
Published: 1 November 2023
...Aarren J. Mannion; Lars Holmgren ABSTRACT The endothelium, the monolayer of endothelial cells that line blood vessels, is exposed to a number of mechanical forces, including frictional shear flow, pulsatile stretching and changes in stiffness influenced by extracellular matrix composition...
Journal Articles
Journal Articles
Dis Model Mech (2017) 10 (9): 1101–1108.
Published: 1 September 2017
... conotruncal abnormality, transposition of the great arteries, is less well understood. In this report, we demonstrate an unexpected role of Pdgfra in endothelial cells and their derivatives during outflow tract development. Loss of Pdgfra in endothelium and endothelial-derived cells results in double outlet...
Includes: Supplementary data