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In collection:Moving Heart Failure to Heart Success
Dis Model Mech (2023) 16 (10): dmm050361.
Published: 1 November 2023
...Aarren J. Mannion; Lars Holmgren ABSTRACT The endothelium, the monolayer of endothelial cells that line blood vessels, is exposed to a number of mechanical forces, including frictional shear flow, pulsatile stretching and changes in stiffness influenced by extracellular matrix composition...
Joanna Suraj, Anna Kurpińska, Agnieszka Zakrzewska, Magdalena Sternak, Marta Stojak, Agnieszka Jasztal, Maria Walczak, Stefan Chlopicki
Dis Model Mech (2019) 12 (3): dmm036269.
Published: 1 March 2019
...Joanna Suraj; Anna Kurpińska; Agnieszka Zakrzewska; Magdalena Sternak; Marta Stojak; Agnieszka Jasztal; Maria Walczak; Stefan Chlopicki ABSTRACT The endothelium plays an important role in cancer metastasis, but the mechanisms involved are still not clear. In the present work, we characterised...
Haig Aghajanian, Young Kuk Cho, Nicholas W. Rizer, Qiaohong Wang, Li Li, Karl Degenhardt, Rajan Jain
Dis Model Mech (2017) 10 (9): 1101–1108.
Published: 1 September 2017
... conotruncal abnormality, transposition of the great arteries, is less well understood. In this report, we demonstrate an unexpected role of Pdgfra in endothelial cells and their derivatives during outflow tract development. Loss of Pdgfra in endothelium and endothelial-derived cells results in double outlet...
Includes: Supplementary data