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Keywords: Endothelial cells
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Journal Articles
Dis Model Mech (2023) 16 (5): dmm049488.
Published: 2 June 2023
... (TGF-β) signaling in endothelial cells. This disorder is characterized by arteriovenous malformations that are prone to rupture, and the ensuing hemorrhages are responsible for iron-deficiency anemia. Along with activin receptor-like kinase ( ALK1 ), mutations in endoglin are associated with the vast...
Includes: Supplementary data
Journal Articles
Dis Model Mech (2022) 15 (12): dmm049753.
Published: 22 December 2022
... on the upright microscope imaging chamber as shown in Fig. 1 J,K. A LaVision Biotec Trimscope II double-header custom multi-photon microscope was used for laser wounding of brain endothelial cells. This was achieved with a Mai Tai HP Ti:Sapphire laser at 785 nm at 50% power and a Zeiss PlanApo 2×water 1.0 N.A...
Includes: Supplementary data
Journal Articles
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Metabolic Disorders
Dis Model Mech (2020) 13 (1): dmm041962.
Published: 24 January 2020
... in atherosclerotic aortas. Furthermore, en face lesion area was increased in macrophage- and endothelial-specific deletions of Ripk3 in the descending and abdominal regions of the aorta . Analysis of bone-marrow-derived macrophages and cultured endothelial cells revealed that Ripk3 deletion promotes expression...
Includes: Supplementary data
Journal Articles
Journal Articles
Dis Model Mech (2014) 7 (6): 683–692.
Published: 1 June 2014
..., and showed strongly reduced mRNA and protein levels for Hif-2α and VEGF; such reduced levels are associated with embryonic endothelial cell apoptosis and lung bleedings. Betamethasone injection in pregnant females prevented respiratory failure in KLEIP −/− neonates, normalized lung maturation...
Includes: Supplementary data