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Keywords: Endoplasmic reticulum stress
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Journal Articles

Propensity to endoplasmic reticulum stress in deer mouse fibroblasts predicts skin inflammation and body weight gain

In collection:
Metabolic Disorders , Tools and Resources for Mouse Studies
Youwen Zhang, Chang-uk Lim, Vitali Sikirzhytski, Asieh Naderi, Ioulia Chatzistamou, Hippokratis Kiaris
Journal: Disease Models & Mechanisms
Dis Model Mech (2021) 14 (10): dmm049113.
https://doi.org/10.1242/dmm.049113
Published: 18 October 2021
... for body weight gain in a manner involving the regulation of an inflammatory response by skin fibroblasts. Endoplasmic reticulum stress Unfolded protein response High-fat diet Inflammation Metabolic disorders National Science Foundation http://dx.doi.org/10.13039/100000001 OIA1736150...
View article titled, Propensity to <span class="search-highlight">endoplasmic</span> <span class="search-highlight">reticulum</span> <span class="search-highlight">stress</span> in deer mouse fibroblasts predicts skin inflammation and body weight gain
Open the PDF for Propensity to <span class="search-highlight">endoplasmic</span> <span class="search-highlight">reticulum</span> <span class="search-highlight">stress</span> in deer mouse fibroblasts predicts skin inflammation and body weight gain in another window
Includes: Supplementary data
Journal Articles

Familial hypercholesterolemia class II low-density lipoprotein receptor response to statin treatment

In collection:
Metabolic Disorders
Linda Omer, Lubna Hindi, Giuseppe Militello, Katlin B. Stivers, Kenneth C. Tien, Nolan L. Boyd
Journal: Disease Models & Mechanisms
Dis Model Mech (2020) 13 (4): dmm042911.
https://doi.org/10.1242/dmm.042911
Published: 6 April 2020
.... , Mansouri , A. , Laurendeau , I. , Cazals-Hatem , D. , Feldmann , G. , Bedossa , P. , Paradis , V. , Martinot-Peignoux , M. , Lebrec , D. , et al. ( 2010 ). In vivo hepatic endoplasmic reticulum stress in patients with chronic hepatitis C . J. Pathol.   221 , 264 - 274...
View article titled, Familial hypercholesterolemia class II low-density lipoprotein receptor response to statin treatment
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Includes: Supplementary data
Journal Articles

Establishment and validation of an endoplasmic reticulum stress reporter to monitor zebrafish ATF6 activity in development and disease

In collection:
Neurodegeneration , Zebrafish as a Disease Model
Eric M. Clark, Hannah J. T. Nonarath, Jonathan R. Bostrom, Brian A. Link
Journal: Disease Models & Mechanisms
Dis Model Mech (2020) 13 (1): dmm041426.
https://doi.org/10.1242/dmm.041426
Published: 28 January 2020
... author of the paper . ATF6 Endoplasmic reticulum stress Unfolded protein response Zebrafish Neurodegeneration The endoplasmic reticulum (ER) is an important organelle in the cell for biosynthesis, folding and maturation of proteins destined for the cell membrane or the extracellular space...
View article titled, Establishment and validation of an <span class="search-highlight">endoplasmic</span> <span class="search-highlight">reticulum</span> <span class="search-highlight">stress</span> reporter to monitor zebrafish ATF6 activity in development and disease
Open the PDF for Establishment and validation of an <span class="search-highlight">endoplasmic</span> <span class="search-highlight">reticulum</span> <span class="search-highlight">stress</span> reporter to monitor zebrafish ATF6 activity in development and disease in another window
Includes: Supplementary data
Journal Articles

SILAC-based quantitative proteomics using mass spectrometry quantifies endoplasmic reticulum stress in whole HeLa cells

Daniel N. Itzhak, Francesca Sacco, Nagarjuna Nagaraj, Stefka Tyanova, Matthias Mann, Marta Murgia
Journal: Disease Models & Mechanisms
Dis Model Mech (2019) 12 (11): dmm040741.
https://doi.org/10.1242/dmm.040741
Published: 11 November 2019
..., distribution and reproduction in any medium provided that the original work is properly attributed. Summary: A novel observation point of a familiar scenario: proteomic quantification of over 6200 proteins as a resource to further explore endoplasmic reticulum stress. Proteomics SILAC Unfolded...
View article titled, SILAC-based quantitative proteomics using mass spectrometry quantifies <span class="search-highlight">endoplasmic</span> <span class="search-highlight">reticulum</span> <span class="search-highlight">stress</span> in whole HeLa cells
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Includes: Supplementary data
Journal Articles

Cellular stress due to impairment of collagen prolyl hydroxylation complex is rescued by the chaperone 4-phenylbutyrate

In collection:
Rare Disease
Roberta Besio, Nadia Garibaldi, Laura Leoni, Lina Cipolla, Simone Sabbioneda, Marco Biggiogera, Monica Mottes, Mona Aglan, Ghada A. Otaify, Samia A. Temtamy, Antonio Rossi, Antonella Forlino
Journal: Disease Models & Mechanisms
Dis Model Mech (2019) 12 (6): dmm038521.
https://doi.org/10.1242/dmm.038521
Published: 20 June 2019
... medium provided that the original work is properly attributed. Editor's choice: Mutations in the collagen 3-prolyl hydroxylation complex cause a cellular stress that is rescued by the chaperone ability of 4-phenylbutyrate. Osteogenesis imperfecta Endoplasmic reticulum stress Chemical...
View article titled, Cellular stress due to impairment of collagen prolyl hydroxylation complex is rescued by the chaperone 4-phenylbutyrate
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Includes: Supplementary data
Journal Articles

Rescue of ATXN3 neuronal toxicity in Caenorhabditis   elegans by chemical modification of endoplasmic reticulum stress

In collection:
Neurodegeneration
Yasmin Fardghassemi, Arnaud Tauffenberger, Sarah Gosselin, J. Alex Parker
Journal: Disease Models & Mechanisms
Dis Model Mech (2017) 10 (12): 1465–1480.
https://doi.org/10.1242/dmm.029736
Published: 1 December 2017
... neuroprotective molecule. Ataxin 3 Caenorhabditis   elegans Endoplasmic reticulum stress Guanabenz Polyglutamine Polyglutamine (poly-Q) expansion diseases are a class of dominantly inherited neurodegenerative disorders that develop when there is an abnormal expansion, and subsequent...
View article titled, Rescue of ATXN3 neuronal toxicity in Caenorhabditis   elegans by chemical modification of <span class="search-highlight">endoplasmic</span> <span class="search-highlight">reticulum</span> <span class="search-highlight">stress</span>
Open the PDF for Rescue of ATXN3 neuronal toxicity in Caenorhabditis   elegans by chemical modification of <span class="search-highlight">endoplasmic</span> <span class="search-highlight">reticulum</span> <span class="search-highlight">stress</span> in another window
Includes: Supplementary data
Journal Articles

Peroxisome proliferator-activated receptor alpha acts as a mediator of endoplasmic reticulum stress-induced hepatocyte apoptosis in acute liver failure

Li Zhang, Feng Ren, Xiangying Zhang, Xinxin Wang, Hongbo Shi, Li Zhou, Sujun Zheng, Yu Chen, Dexi Chen, Liying Li, Caiyan Zhao, Zhongping Duan
Journal: Disease Models & Mechanisms
Dis Model Mech (2016) 9 (7): 799–809.
https://doi.org/10.1242/dmm.023242
Published: 1 July 2016
..., its regulatory mechanisms remain largely undetermined. Endoplasmic reticulum stress (ER stress) plays an important role in a number of liver diseases. This study aimed to investigate whether PPARα activation inhibits ER stress-induced hepatocyte apoptosis, thereby protecting against ALF. In a murine...
View article titled, Peroxisome proliferator-activated receptor alpha acts as a mediator of <span class="search-highlight">endoplasmic</span> <span class="search-highlight">reticulum</span> <span class="search-highlight">stress</span>-induced hepatocyte apoptosis in acute liver failure
Open the PDF for Peroxisome proliferator-activated receptor alpha acts as a mediator of <span class="search-highlight">endoplasmic</span> <span class="search-highlight">reticulum</span> <span class="search-highlight">stress</span>-induced hepatocyte apoptosis in acute liver failure in another window
Includes: Supplementary data
Journal Articles

ER stress and basement membrane defects combine to cause glomerular and tubular renal disease resulting from Col4a1 mutations in mice

Frances E. Jones, Matthew A. Bailey, Lydia S. Murray, Yinhui Lu, Sarah McNeilly, Ursula Schlötzer-Schrehardt, Rachel Lennon, Yoshikazu Sado, David G. Brownstein, John J. Mullins, Karl E. Kadler, Tom Van Agtmael
Journal: Disease Models & Mechanisms
Dis Model Mech (2016) 9 (2): 165–176.
https://doi.org/10.1242/dmm.021741
Published: 1 February 2016
... , Y. and Miner , J. H. ( 2013 ). Laminin beta2 gene missense mutation produces endoplasmic reticulum stress in podocytes . J. Am. Soc. Nephrol.   24 , 1223 - 1233 . 10.1681/ASN.2012121149 Chen , Z. , Migeon , T. , Verpont , M.-C. , Zaidan , M. , Sado , Y...
View article titled, ER stress and basement membrane defects combine to cause glomerular and tubular renal disease resulting from Col4a1 mutations in mice
Open the PDF for ER stress and basement membrane defects combine to cause glomerular and tubular renal disease resulting from Col4a1 mutations in mice in another window
Includes: Supplementary data