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Keywords: Endolysosomal system
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Journal Articles
Lin Song, Ramesh Rijal, Malte Karow, Maria Stumpf, Oliver Hahn, Laura Park, Robert Insall, Rolf Schröder, Andreas Hofmann, Christoph S. Clemen, Ludwig Eichinger
Journal:
Disease Models & Mechanisms
Dis Model Mech (2018) 11 (9): dmm033449.
Published: 13 September 2018
... and exocytosis of indigestible material. Our results underscore a key role for the WASH complex and its core subunit, Str, in the endolysosomal system, and highlight the fundamental importance of the Str N471 residue for maintaining lysosome morphology and dynamics. Our data indicate that the SPG8-causing N471D...
Includes: Supplementary data
