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Keywords: EIF2AK2
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Journal Articles
Samuel B. Burnett, Allison M. Culver, Tricia A. Simon, Taylor Rowson, Kenneth Frederick, Kristina Palmer, Stephen A. Murray, Shannon W. Davis, Rekha C. Patel
Journal:
Disease Models & Mechanisms
Dis Model Mech (2024) 17 (11): dmm050929.
Published: 26 November 2024
... with disruption of coordinated muscle movements. PACT and its murine homolog RAX activate protein kinase R (PKR; also known as EIF2AK2) by a direct interaction in response to cellular stressors to mediate phosphorylation of the α subunit of eukaryotic translation initiation factor 2 (eIF2α). Mice homozygous...
Includes: Supplementary data
